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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SREK1 / SRRP86 Antibody (aa409‑424) IHC‑plus™ LS‑B3093 Best Seller
Note: This antibody replaces LS-C10331
SRRP86 antibody LS-B3093 is an unconjugated rabbit polyclonal antibody to SRRP86 (SREK1) from human, bat, dog and other species. Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3093-50
50 µg (0.3 mg/ml)
Unavailable

Popular SREK1 / SRRP86 Products

SREK1 / SFRS12 antibody LS-C111341 Western blot of HT1080 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bovine, Guinea pig, Rabbit
Applications: Western blot
Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 C: U87-MG 7.5% SDS PAGE SREK1 / SFRS12 antibody diluted at 1:1000
Species: Human
Applications: Western blot
SREK1 / SFRS12 antibody LS-C111341 Western blot of HT1080 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Gibbon, Monkey, Bovine, Guinea pig, Rabbit
Applications: Western blot
SREK1 / SFRS12 antibody LS-C111341 Western blot of HT1080 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Gibbon, Monkey, Bovine, Guinea pig, Rabbit
Applications: Western blot

Product Description

SRRP86 antibody LS-B3093 is an unconjugated rabbit polyclonal antibody to SRRP86 (SREK1) from human, bat, dog and other species. Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
About SREK1 / SRRP86
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3. Q8WXA9 NM_139168 NP_631907.1

SREK1 Antibody, SFRS12 Antibody, SRrp508 Antibody, SRrp86 Antibody


Specifications

Target
Human SREK1 / SRRP86
Host
Rabbit
Reactivity
Human, Monkey, Bat, Dog, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Hamster, Rabbit (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SREK1 / SRRP86 antibody was raised against synthetic peptide aa409-424, PRSRNKKDKKREKERD of human SFRS12 (KLH). MW: 59380kD. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Panda, Dog, Bat, Horse, Pig (100%); Hamster, Elephant, Rabbit (94%); Mouse, Rat (88%); Lizard, Stickleback (81%).
Epitope
aa409-424
Specificity
Recognizes human Splicing Factor, Arginine/Serine-Rich 12. Species cross-reactivity: rodent.
Usage
Immunohistochemistry: LS-B3093 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3093 was determined to be 5 ug/ml. Western Blot: Preliminary results: MCF7 cells 110kD, Human breast 70kD (weak).
Presentation
PBS, pH 7.2, 40% glycerol.
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.

Immunohistochemistry

Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.
Anti-SREK1 / SFRS12 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3093 concentration 5 ug/ml.


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Date Requested: 6/25/2018

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