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Anti-SPN / CD43 Antibody LS-C13408

Ordering

Wt. Vol. Conc. Price
- 1000 µl - $905
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Mouse Monoclonal (IgG1) to Human SPN / CD43
Human
IHC - Paraffin, IHC - Frozen
Unconjugated

Details

Human SPN / CD43
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Tissue culture supernatant

Applications

IHC - Paraffin, IHC - Frozen (1:10 - 1:40)

Specificity and Use

SPN / CD43 antibody was raised against human lymph node cells.
Recognizes the human CD43 cell surface antigen. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma. CD43 has been used widely as a useful marker of T cells lymphomas in formalin fixed tissues.
Immunohistochemistry: (frozen)- 1:10-1:40, (paraffin)- 1:10-1:40. Positive control: Human Tonsil.

Packaging

Tissue Culture Supernatant. Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SPN / CD43

P16150 NM_003123 NP_003114.1

SPN Antibody, GPL115 Antibody, Leukosialin Antibody, Leukocyte sialoglycoprotein Antibody, Galactoglycoprotein Antibody, GALGP Antibody, Sialophorin Antibody, LSN Antibody, CD43 Antibody, CD43 antigen Antibody

One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity).

Requested From: United States
Date Requested: 9/26/2016

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