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Anti-SPEN / SHARP Antibody (aa1503-1517) LS-C55521

Catalog Size Price
LS-C55521-100 100 µg Unavailable

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2 SPEN / SHARP Antibodies

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Anti-SPEN / SHARP Antibody (aa1503-1517) LS-C55521
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Anti-SPEN / SHARP Antibody (aa1350-1400) LS-C287946
Rabbit Polyclonal (IgG) to Human SPEN / SHARP
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Anti-SPEN / SHARP Antibody (aa3375-3425) LS-C287948
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100% Guaranteed
Goat Polyclonal to Human SPEN / SHARP
Human, Monkey


Human, Monkey (tested or 100% immunogen sequence identity)
Bovine, Dog, Horse, Rabbit (at least 90% immunogen sequence identity)
Immunoaffinity purified


ELISA (1:4000)
IHC - Paraffin

Specificity and Use

SPEN / SHARP antibody was raised against synthetic peptide C-DSEGKMDDKKEDHKE from an internal region of human SPEN (NP_055816.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Panda, Bovine, Dog, Horse, Rabbit (93%); Hamster, Elephant, Bat (87%); Xenopus (80%).
LS-E26058 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55521. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human SPEN.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.


Q96T58 NM_015001 NP_055816.2

SPEN Antibody, HIAA0929 Antibody, Msx2-interacting protein Antibody, KIAA0929 Antibody, RBM15C Antibody, Mint Antibody, RP1-134O19.1 Antibody, SHARP Antibody, SPEN homolog Antibody

May serve as a nuclear matrix platform that organizes and integrates transcriptional responses. In osteoblasts, supports transcription activation: synergizes with RUNX2 to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Has also been shown to be an essential corepressor protein, which probably regulates different key pathways such as the Notch pathway.

Requested From: 
Date Requested: 12/18/2017

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