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Anti-SOCS7 / SOCS-7 Antibody (aa10-22) LS-C87362

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SOCS7 / SOCS-7 Antibodies

Anti-SOCS7 / SOCS-7 Antibody (aa458-486, AP) LS-C269935
Rabbit Polyclonal (IgG) to Human SOCS7 / SOCS-7
Human
Western blot, ELISA
AP Conjugated
Anti-SOCS7 / SOCS-7 Antibody (aa458-486, Azide-free, HRP) LS-C269938
Rabbit Polyclonal (IgG) to Human SOCS7 / SOCS-7
Human
Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human SOCS7 / SOCS-7
Human
Western blot, ELISA
Unconjugated

Details

Human SOCS7 / SOCS-7
Goat
Human (tested or 100% immunogen sequence identity)
Monkey, Rat, Bat, Bovine, Dog, Horse, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1 - 3 µg/ml)
  • ELISA (1:32000) & (1 - 3 µg/ml)

Specificity and Use

SOCS7 / SOCS-7 antibody was raised against synthetic peptide C-DAGRKPKLTRTQS from an internal region of human SOCS7 (NP_055413.1). Percent identity by BLAST analysis: Human, Gibbon (100%); Monkey, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit (92%); Mouse, Pig (85%).
LS-E26876 - Lyophilized - 100 µg - $145.00
aa10-22
Human SOCS7.
Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx. 60kD band observed in lysates of Daudi (calculated MW of 63.0kD according to NP_055413.1). Recommended concentration: 1-3 ug/ml. An additional band of unknown identity was also consistently observed at 28kD. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SOCS7 / SOCS-7

O14512 AB005216 BAA22432.1

SOCS7 Antibody, NAP-4 Antibody, Nck-associated protein 4 Antibody, SOCS-7 Antibody, NAP4 Antibody, NCKAP4 Antibody

Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.

Western blot

Western blot
Antibody (1 ug/ml) staining of Daudi lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
 

Requested From: United States
Date Requested: 12/8/2016

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