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Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Gene Name: | small nuclear ribonucleoprotein 70kDa (U1) |
Synonyms: | SNRNP70, SNRP70, Snp1, U170K, U1AP1, U1 snRNP 70 kDa, U1-70K, U1RNP, RPU1, RNPU1Z, U1AP |
Target Sequences: | NM_003089 NP_003080.2 P08621 |
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