Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (1:10000 - 1:100000)
Synthetic 18-aa peptide near the C-terminus of rat g-synuclein coupled with KLH.
Recognizes rat g-Synclein. The rat peptide sequence is 100% conserved in mouse g-synuclein. No significant sequence homology is seen with either human g-synuclein or synucleins-alpha or beta or other proteins.
Suitable for use in ELISA, Western Blot and Immunoprecipitation. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well. Western Blot:1-10 ug/ml (ECL). Immunoprecipitation: 1-10 ug affinity/100 ug of tissue.
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.