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Anti-SNCAIP / Synphilin 1 Antibody (aa829-847) LS-C11522

Note: This antibody replaces LS-C86249, LS-C26318, LS-C122462
Catalog Size Price
LS-C11522-100 100 µl Unavailable

Most Popular SNCAIP / Synphilin 1 Antibodies

Anti-SNCAIP / Synphilin 1 Antibody (C-Terminus) LS-C353186
Rabbit Polyclonal to Human SNCAIP / Synphilin 1
Human
IHC, IHC - Paraffin, Western blot
Unconjugated
Immunohistochemical analysis of Synphilin 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Anti-SNCAIP / Synphilin 1 Antibody (Biotin) LS-C687514
Rabbit Polyclonal to Rat SNCAIP / Synphilin 1
Rat
IHC, Western blot
Biotin Conjugated
Western Blot; Sample: Recombinant protein.
Anti-SNCAIP / Synphilin 1 Antibody (FITC) LS-C694349
Rabbit Polyclonal to Rat SNCAIP / Synphilin 1
Rat
IHC, Western blot
FITC Conjugated
Western Blot; Sample: Recombinant protein.
Anti-SNCAIP / Synphilin 1 Antibody (Cy3) LS-C702964
Rabbit Polyclonal to Rat SNCAIP / Synphilin 1
Rat
IHC, Western blot
Cy3 Conjugated
Western Blot; Sample: Recombinant protein.
Anti-SNCAIP / Synphilin 1 Antibody (HRP) LS-C711989
Rabbit Polyclonal to Rat SNCAIP / Synphilin 1
Rat
IHC, Western blot
HRP Conjugated
Western Blot; Sample: Recombinant protein.

100% Guaranteed
Goat Polyclonal (IgG) to Human SNCAIP / Synphilin 1
Human, Monkey, Dog
IHC, IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human SNCAIP / Synphilin 1
Goat
Human, Monkey, Dog (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC
  • IHC - Paraffin (1:400)
  • Western blot (1:2000)
  • ELISA (1:5000)

Specificity and Use

Peptide 829SLELNGEKDKDKGRTLQRT847. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog (100%); Bat, Horse (89%); Mouse, Bovine (84%).
aa829-847
Recognizes synphilin-1, a cytoplasmic protein which associates with alpha-synuclein in vivo. Alpha-Synuclein is a major component of Lewy bodies in patients with sporadic Parkinson's disease (PD) and mutations of alpha-synuclein are involved in familial forms of PD. Reports suggest that synphilin-1 may play a role in Lewy body formation in association with alpha synuclein.

Packaging

Serum, 0.09% sodium azide.
For research use only.

About SNCAIP / Synphilin 1

Q9Y6H5 NM_005460 NP_005451.2

SNCAIP Antibody, Synphilin-1 Antibody, SYPH1 Antibody, SPH1 Antibody, Synphilin 1 Antibody

Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.

Requested From: 
Date Requested: 5/24/2018

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