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Anti-SNCAIP / Synphilin 1 Antibody (aa829-847) LS-C11522

Note: This antibody replaces LS-C86249, LS-C26318, LS-C122462

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SNCAIP / Synphilin 1 Antibodies

Anti-SNCAIP / Synphilin 1 Antibody (aa829-847) LS-C26321
Rabbit Polyclonal (IgG) to Human SNCAIP / Synphilin 1
Human, Rat
IHC, Western blot
Unconjugated
Anti-SNCAIP / Synphilin 1 Antibody LS-C89916
Rabbit Polyclonal to Human SNCAIP / Synphilin 1
Human, Monkey, Mouse, Dog
IHC
Unconjugated
Anti-SNCAIP / Synphilin 1 Antibody LS-C89917
Rabbit Polyclonal to Human SNCAIP / Synphilin 1
Human, Rat
IHC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human SNCAIP / Synphilin 1
Human, Monkey, Dog
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human SNCAIP / Synphilin 1
Goat
Human, Monkey, Dog (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC - Paraffin (1:400)
  • Western blot (1:2000)
  • ELISA (1:5000)

Specificity and Use

SNCAIP / Synphilin 1 antibody was raised against peptide 829SLELNGEKDKDKGRTLQRT847. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog (100%); Bat, Horse (89%); Mouse, Bovine (84%).
aa829-847
Recognizes synphilin-1, a cytoplasmic protein which associates with alpha-synuclein in vivo. Alpha-Synuclein is a major component of Lewy bodies in patients with sporadic Parkinson's disease (PD) and mutations of alpha-synuclein are involved in familial forms of PD. Reports suggest that synphilin-1 may play a role in Lewy body formation in association with alpha synuclein.

Packaging

Serum, 0.09% sodium azide.
For research use only.

About SNCAIP / Synphilin 1

Q9Y6H5 NM_005460 NP_005451.2

SNCAIP Antibody, Synphilin-1 Antibody, SYPH1 Antibody, SPH1 Antibody, Synphilin 1 Antibody

Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.

Requested From: United States
Date Requested: 12/10/2016

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