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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SMC1A / SMC1 Antibody (aa916-927)

SMC1 antibody LS-C17946 is an unconjugated rabbit polyclonal antibody to SMC1 (SMC1A) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C17946-200
200 µg
$560
Description
SMC1 antibody LS-C17946 is an unconjugated rabbit polyclonal antibody to SMC1 (SMC1A) from human, mouse, rat and other species. Validated for WB.
Target
Human SMC1A / SMC1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Pig, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
SMC1A / SMC1 antibody was raised against kLH-conjugated, synthetic peptide corresponding to amino acids 916-927 of human SMC1 (C-ETKLEQKRSDRH) with a N-terminal cysteine. The immunizing sequence is identical in rat, bovine and Xenopus and has 11/12 identical amino acids in mouse. Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Chicken, Lizard, Xenopus, Stickleback, Pufferfish, Zebrafish (100%); Trichina worm (83%).
Epitope
aa916-927
Specificity
Recognizes SMC1, Mr 150kD. Additional proteins are detected at Mr 45kD and 140kD. All three proteins are competed by the immunizing peptide. Species cross-reactivity: Human. Predicted to cross-react with rat, bovine and Xenopus based on sequence homology.
Usage
Western Blot: 2 ug/ul.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About SMC1A / SMC1
Q14683 NM_006306 NP_006297.2

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Requested From: United States
Date Requested: 1/23/2019
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