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Anti-SMAD7 Antibody (aa195-224) LS-C161302


Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SMAD7 Antibodies

Anti-SMAD7 Antibody (aa36-50) IHC-plus™ LS-B120
Rabbit Polyclonal (IgG) to Human SMAD7
Human, Monkey, Bat, Bovine, Dog
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-SMAD7 Antibody (clone 293039) LS-C150142
Mouse Monoclonal [clone 293039] (IgG2b) to Human SMAD7
Human, Mouse, Rat
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-SMAD7 Antibody (aa375-389) LS-C313088
Rabbit Polyclonal (IgG) to Human SMAD7
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SMAD7
IHC - Paraffin, Immunofluorescence, Western blot


Human SMAD7
Human (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation


  • IHC - Paraffin (1:10 - 1:50)
  • Immunofluorescence (1:10 - 1:50)
  • Western blot (1:1000)

Specificity and Use

SMAD7 antibody was raised against kLH-conjugated synthetic peptide between amino acids 195-224 from internal region of human Smad7.
LS-E8438 - Lyophilized - 100 µg - $145.00
Human SMAD7


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About SMAD7

O15105 NM_005904 NP_005895.1

SMAD7 Antibody, CRCS3 Antibody, HSMAD7 Antibody, MAD homolog 7 Antibody, SMAD 7 Antibody, MADH7 Antibody, MADH8 Antibody, Mothers against DPP homolog 7 Antibody, Mothers against DPP homolog 8 Antibody, MAD homolog 8 Antibody, SMAD family member 7 Antibody

Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation.


Smad7 Antibody IHC of formalin-fixed and paraffin-embedded lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.


Fluorescent confocal image of A431 cell stained with Smad7 Antibody. A431 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with Smad7 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). Smad7 immunoreactivity is localized to cytoplasm significantly.

Western blot

Western blot
Western blot of Smad7 Antibody in ZR-75-1 cell line lysates (35 ug/lane). Smad7 (arrow) was detected using the purified antibody.

Requested From: United States
Date Requested: 10/27/2016

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