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Anti-SMAD7 Antibody (aa12-29, Azide-free) LS-C147986

Ordering

Wt. Vol. Conc. Price
100 µg - - $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SMAD7 Antibodies

Anti-SMAD7 Antibody (aa36-50) IHC-plus™ LS-B120
Rabbit Polyclonal (IgG) to Human SMAD7
Human, Monkey, Bat, Bovine, Dog
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SMAD7 Antibody (clone 293039) LS-C150142
Mouse Monoclonal [clone 293039] (IgG2b) to Human SMAD7
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SMAD7 Antibody (aa375-389) LS-C313088
Rabbit Polyclonal (IgG) to Human SMAD7
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SMAD7
Human, Monkey, Bat, Bovine, Dog
Western blot
Unconjugated, Azide-free

Details

Human SMAD7
Rabbit
Human, Monkey, Bat, Bovine, Dog (tested or 100% immunogen sequence identity)
Mouse, Rat, Pig, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein G purified
Azide-free

Applications

Western blot (4 - 6 µg/ml)

Specificity and Use

SMAD7 antibody was raised against amino acids 12-29 (RLWRSRAPGGEDEEEGAG) and amino acids 36-50 (ELRGEGATDSRAHGA) of human SMAD7. This sequence is 100% or highly conserved between human and multiple species. Percent identity by BLAST analysis: Human, Monkey, Bovine, Dog, Bat, Panda (100%); Mouse, Rat, Rabbit, Pig, Platypus (94%).
aa12-29
In A549, an approx. 45 kD band is observed. This may cross-react with SMAD6 depending on cell or tissue-specific expression.
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Packaging

PBS, azide-free, sterile filtered
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About SMAD7

O15105 NM_005904 NP_005895.1

SMAD7 Antibody, CRCS3 Antibody, HSMAD7 Antibody, MAD homolog 7 Antibody, SMAD 7 Antibody, MADH7 Antibody, MADH8 Antibody, Mothers against DPP homolog 7 Antibody, Mothers against DPP homolog 8 Antibody, MAD homolog 8 Antibody, SMAD family member 7 Antibody

Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation.

Requested From: United States
Date Requested: 12/3/2016

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