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Anti-SLC6A4 / SERT Antibody (Extracellular Domain) LS-C39063

Catalog Size Price
LS-C39063-50 50 µg Unavailable

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63 SLC6A4 / SERT Antibodies

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100% Guaranteed
Rabbit Polyclonal (IgG) to Rat SLC6A4 / SERT
Rat, Human
Western blot, ELISA
Unconjugated

Details

Rat SLC6A4 / SERT
Rabbit
Rat, Human (tested or 100% immunogen sequence identity)
Mouse, Guinea pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1 - 10 µg/ml)
  • ELISA (0.5 - 1 µg/ml)

Specificity and Use

SLC6A4 / SERT antibody was raised against synthetic peptide 15aa sequence between transmembrane domain 7 and 8 of rat serotonin transporter (KLH coupled). This region is presumably from the extracellular domain.
Extracellular Domain
Recognizes Rat Serotonin Transporter. Species cross-reactivity: Human. Species sequence Homology: Human, monkey, mouse: 100%; guinea pig: 93%.
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml (ECL). Antibody activity may be reduced considerably when detecting endogenous SERT from rat or human cells. SERT has been observed to migrate as 94kD (rat platelet), 80kD (pulmonary membranes), and 76kD (rat brain). This could be due to differences in post translational modifications (e. g., glycosylation). ELISA: 0.5-1 ug/ml. Coat ELISA plates with 50-100 ng SERT control peptide/well.

Packaging

PBS, pH 7.4, 0.1% BSA, 40% glycerol.
For research use only.

About SLC6A4 / SERT

P31645 NM_001045 NP_001036.1

SLC6A4 Antibody, 5HTT Antibody, 5HT transporter Antibody, 5-HTT Antibody, 5-HTTLPR Antibody, OCD1 Antibody, SERT Antibody, Serotonin transporter Antibody, HSERT Antibody, SERT1 Antibody

SLC6A4 / SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family.

Requested From: 
Date Requested: 6/26/2017

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