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Anti-SLC19A1 Antibody (aa10-23) LS-C139788

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $275
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SLC19A1 Antibodies

Anti-SLC19A1 Antibody (N-Terminus) LS-C40455
Rabbit Polyclonal (IgG) to Human SLC19A1
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SLC19A1 Antibody (N-Terminus) LS-C129136
Rabbit Polyclonal (IgG) to Rat SLC19A1
Rat
Western blot, ELISA
Unconjugated
Anti-SLC19A1 Antibody (aa10-23) LS-C139788
Goat Polyclonal to Mouse SLC19A1
Mouse
ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Mouse SLC19A1
Mouse
ELISA
Unconjugated

Details

Mouse SLC19A1
Goat
Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

ELISA (1:128000)

Specificity and Use

SLC19A1 antibody was raised against synthetic peptide KQAYEEPRQDHELK-C from the N-terminus of mouse SLC19A1 (NP_112473.1). Percent identity with other species by BLAST analysis: Mouse (100%), Rat (86%), Hamster (86%).
LS-E27693 - Lyophilized - 100 µg - $145.00
aa10-23
Mouse SLC19A1.
Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Preliminary experiments gave bands at approx 65kD and 26kD in Mouse Skin lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 58.2kD according to NP_112473.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SLC19A1

P41440 NM_194255 NP_919231.1

SLC19A1 Antibody, CHMD Antibody, IFC1 Antibody, Folate transporter 1 Antibody, FOLT Antibody, IFC-1 Antibody, Intestinal folate carrier 1 Antibody, Reduced folate transporter Antibody, REFC Antibody, Folate transporter Antibody, Intestinal folate carrier Antibody, Placental folate transporter Antibody, Reduced folate carrier 1 Antibody, Reduced folate carrier protein Antibody, RFC Antibody

Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.

Requested From: United States
Date Requested: 12/3/2016

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