Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SLC18A3 / VACHT antibody was raised against synthetic peptide from the C-terminal of rat VAChT conjugated to BSA. Works on rat and mouse tissues. Positive control: Frozen sections of rat small intestine. Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes the staining.
50 µl Distilled water
Prior to reconstitution, +4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
SLC18A3 / VACHT is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.