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SLC15A1 / PEPT1 is an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.
Gene Name: | solute carrier family 15 (oligopeptide transporter), member 1 |
Family/Subfamily: | Transporter , Proton-dependent oligopeptide transporter |
Synonyms: | SLC15A1, HPECT1, PEPT1, HPEPT1, Peptide transporter 1 |
Target Sequences: | NM_005073 NP_005064.1 P46059 |
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