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Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K+ uptake into Deiters' cells in the cochlea and contribute to K+ recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl- extrusion in the kidney and contribute to renal acidification.
Gene Name: | solute carrier family 12 (potassium/chloride transporter), member 7 |
Family/Subfamily: | Transporter , Cation:chloride symporter |
Synonyms: | SLC12A7, DKFZP434F076, K-Cl cotransporter 4, KCC4 |
Target Sequences: | NM_006598 NP_006589.2 Q9Y666 |
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