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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC12A6 / KCC3 Antibody (C‑Terminus) LS‑C16127
KCC3 antibody LS-C16127 is an unconjugated rabbit polyclonal antibody to KCC3 (SLC12A6) from human, rat and rabbit. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C16127-100
100 µl
$725

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Product Description

KCC3 antibody LS-C16127 is an unconjugated rabbit polyclonal antibody to KCC3 (SLC12A6) from human, rat and rabbit. Validated for ELISA and WB.
About SLC12A6 / KCC3
SLC12A6 / KCC3 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Q9UHW9 NM_005135 NP_005126.1

SLC12A6 Antibody, ACCPN Antibody, KCC3A Antibody, KCC3 Antibody, K-Cl cotransporter 3 Antibody, KCC3B Antibody


Specifications

Target
Rat SLC12A6 / KCC3
Host
Rabbit
Reactivity
Rat, Human, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:250 - 1:500)
  • ELISA (1:5000 - 1:50000)
Immunogen
SLC12A6 / KCC3 antibody was raised against a 17 AA peptide within the cytoplasmic, c-terminal domain of the rat NHE4 (1) was used selected for antibody production.
Epitope
C-Terminus
Specificity
Recognizes human KCC3 and KCC-3b spliced form. Species sequence Homology: rat-89%, mouse-78% (KCC3b).
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:250-1:500. Band seen at 95-110kD (brush border membrane). ELISA: 1:5000-1:50000. Control peptide can be used to coat ELISA plates at 1 ug/ml.
Presentation
PBS, 0.05% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/16/2018

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