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Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Gene Name: | Src-like-adaptor 2 |
Family/Subfamily: | Protein Kinase Non Catalytic , not assigned-Protein Kinase Non Catalytic |
Synonyms: | SLA2, SLAP2, Src-like-adapter 2, Src-like-adaptor 2, Src-like adapter protein-2, C20orf156, SLAP-2, Src-like adapter protein 2 |
Target Sequences: | NM_032214 NP_115590.1 Q9H6Q3 |
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