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Mouse SIX3 | |
Rabbit | |
Mouse, Human, Monkey, Rat, Bovine, Guinea pig (tested or 100% immunogen sequence identity) | |
Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, FITC, HRP. | |
Immunoaffinity purified | |
Unmodified |
SIX3 antibody was raised against synthetic peptide from C-Terminus of mouse Six3 (Q62233, NP_035511). Percent identity by BLAST analysis: Human, Chimpanzee, Galago, Marmoset, Mouse, Rat, Bovine, Opossum, Guinea pig (100%); Chicken, Xenopus, Zebrafish (92%). | ||
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C-Terminus | ||
Mouse SIX3 | ||
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
SIX3 Antibody, HPE2 Antibody, Sine oculis homeobox homolog 3 Antibody, SIX homeobox 3 Antibody, Homeobox protein SIX3 Antibody
Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon.
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