Products

Antibodies
All Antibodies
Primary Antibodies
Secondary Antibodies
IHC-plus Antibodies
Isotype Control Antibodies

ELISA and Assay Kits
All Kits
Assay Kits
Traditional ELISA Kits
Cell-Based ELISA Kits
DNA-Binding ELISA Kits
Phospho-Specific ELISA Kits
ELISA Development Kits
Chemiluminescent CLIA Kits

Proteins
All Proteins
Recombinant Proteins
Native Proteins
Over-expression Lysates
Cell and Tissue Lysates
Bio-active Proteins
Animal-free Proteins
Synthetic Peptides

Biochemicals
All Biochemicals

Immunohistochemistry
Comprehensive IHC Reports
Custom IHC Services
TCR Screening Services
IHC-plus Antibodies

Services

Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Have a question? CustomerSupport@LSBio.com

Resources

Purchasing
Product Ordering Terms and Conditions
Holiday Schedule
About the LSBio Guarantee
About Our Rewards Program

Reference Material
About LSBio (LifeSpan BioSciences Inc.)
About Our 2-million Specimen Tissue Bank
About Our IHC Validation Process
About Our IHC-plus™ Immunohistochemistry Protocol
Protocols

Secure Logins
Login to Our Secure ShareFile Site
Login to Our IHC Database

Distributors

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone:	866-819-4732 (Toll Free North America) 206-374-1102 (International)

Fax:	866-206-6909 (Toll Free North America) 206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.

Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.

Login Name:
Password:

Forgot password?

Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.

Login Name*:
Email*:
Password*:
Confirm Password*:
Name:
Organization:
Role:

Fields marked with a * are required.

Wish List

View Cart

Anti-SIX3 Antibody (C-Terminus) LS-C116055

Catalog	Size	Price
LS-C116055-50	50 µg	Unavailable

Related Products

19 SIX3 Antibodies

Most Popular SIX3 Antibodies

Anti-SIX3 Antibody (clone 3D12) LS-C198201

Antibody:	Mouse Monoclonal [clone 3D12] (IgG2a,k) to Human SIX3
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-SIX3 Antibody (aa138-166, AP) LS-C217530

Antibody:	Rabbit Polyclonal (IgG) to Human SIX3
Reactivity:	Human
Application:	Western blot, ELISA
Format:	AP Conjugated

Anti-SIX3 Antibody (aa138-166, APC) LS-C217533

Antibody:	Rabbit Polyclonal (IgG) to Human SIX3
Reactivity:	Human
Application:	Western blot, ELISA
Format:	APC Conjugated

Anti-SIX3 Antibody (aa138-166, Biotin) LS-C217534

Antibody:	Rabbit Polyclonal (IgG) to Human SIX3
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Biotin Conjugated

Anti-SIX3 Antibody (aa137-166) LS-C325128

Antibody:	Rabbit Polyclonal (IgG) to Human SIX3
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Mouse SIX3
Reactivity:	Mouse, Human, Monkey, Rat, Bovine, Guinea pig
Application:	Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Mouse SIX3
Host:	Rabbit
Reactivity:	Mouse, Human, Monkey, Rat, Bovine, Guinea pig (tested or 100% immunogen sequence identity)
Predicted:	Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot (0.2 - 1 µg/ml)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:

SIX3 antibody was raised against synthetic peptide from C-Terminus of mouse Six3 (Q62233, NP_035511). Percent identity by BLAST analysis: Human, Chimpanzee, Galago, Marmoset, Mouse, Rat, Bovine, Opossum, Guinea pig (100%); Chicken, Xenopus, Zebrafish (92%).

Blocking Peptide:

LS-E13321 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C116055. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

C-Terminus

Specificity:

Mouse SIX3

Usage:

Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Presentation:	Lyophilized from PBS with 2% sucrose
Reconstitution:	Distilled water
Storage:	Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About SIX3

Uniprot: O95343 NCBI: NM_005413 NP_005404.1

Synonyms: SIX3 Antibody, HPE2 Antibody, Sine oculis homeobox homolog 3 Antibody, SIX homeobox 3 Antibody, Homeobox protein SIX3 Antibody

Description: Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon.

(More About SIX3)

Print This Page Email

Technical Help Review

Review This Product

Western blot

SIX3 antibody LS-C116055 Western blot of Mouse Thymus lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 8/20/2017

Get Social With Us!

Catalog Number