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Anti-SIRT6 / Sirtuin 6 Antibody (C-Terminus) LS-C75839

Catalog Size Price
LS-C75839-100 100 µl Unavailable

Most Popular SIRT6 / Sirtuin 6 Antibodies

Anti-SIRT6 / Sirtuin 6 Antibody (aa305-320) IHC-plus™ LS-B900
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Anti-SIRT6 / Sirtuin 6 Antibody (aa290-319) LS-C100492
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Anti-SIRT6 / Sirtuin 6 Antibody (C-Terminus) IHC-plus™ LS-B5588
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Anti-SIRT6 / Sirtuin 6 Antibody (aa56-105) IHC-plus™ LS-B5589
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human SIRT6 / Sirtuin 6
Human
Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated

Details

Human SIRT6 / Sirtuin 6
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Immunofluorescence
  • Western blot (1:1000)
  • Immunoprecipitation (1:50)

Specificity and Use

Synthetic peptide (KLH-coupled) corresponding to the carboxy terminus of the human SirT6 protein.
C-Terminus
Detects endogenous levels of human total SirT6 protein at 42kD. This antibody does not cross-react with other sirtuin proteins.
Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Immunofluorescence: (IC) 1:100. Western Blot: 1:1000. Immunoprecipitation: 1:50.

Packaging

10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol.
For research use only.

About SIRT6 / Sirtuin 6

Q8N6T7 NM_016539 NP_057623.2

SIRT6 Antibody, SIR2-like protein 6 Antibody, Sirtuin type 6 Antibody, SIR2L6 Antibody, Sir2-related protein type 6 Antibody, Sirtuin 6 Antibody

NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis.

Requested From: 
Date Requested: 12/16/2017

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