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Anti-SIRT6 / Sirtuin 6 Antibody (C-Terminus, DY488) LS-C141044

Ordering

Wt. Vol. Conc. Price
- 100 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SIRT6 / Sirtuin 6 Antibodies

Anti-SIRT6 / Sirtuin 6 Antibody (aa250-334) LS-C49020
Rabbit Polyclonal to Mouse SIRT6 / Sirtuin 6
Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SIRT6 / Sirtuin 6 Antibody (C-Terminus) IHC-plus™ LS-B5588
Rabbit Polyclonal to Human SIRT6 / Sirtuin 6
Human, Rat, Bovine, Dog
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SIRT6 / Sirtuin 6 Antibody (aa56-105) IHC-plus™ LS-B5589
Rabbit Polyclonal (IgG) to Human SIRT6 / Sirtuin 6
Human, Monkey, Mouse, Bat, Dog, Hamster, Pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse SIRT6 / Sirtuin 6
Mouse
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
DY488 Conjugated

Details

Mouse SIRT6 / Sirtuin 6
Rabbit
Mouse (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Polyclonal
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Affinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (2 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

SIRT6 / Sirtuin 6 antibody was raised against a synthetic peptide made to a C-terminal region of the mouse SIRT6 protein (within residues 250-334). [Swiss-Prot P59941] Percent identity by BLAST analysis: Rat (92%); Human (78%).
C-Terminus
SIRT6.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Store at 4°C. Do not freeze.
For research use only.

About SIRT6 / Sirtuin 6

Q8N6T7 NM_016539 NP_057623.2

SIRT6 Antibody, SIR2-like protein 6 Antibody, Sirtuin type 6 Antibody, SIR2L6 Antibody, Sir2-related protein type 6 Antibody, Sirtuin 6 Antibody

NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis.

Immunohistochemistry

Immunohistochemistry
Detection of SIRT6 in MEF lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/6/2016

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