Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 15-414] (IgG2a) to Human SIRPA / CD172a
Human SIRPA / CD172a
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [15-414]
Specificity and Use
SIRPA / CD172a antibody was raised against human SIRPA
This 15-414 antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood cells. This can be used at 5 ul (0.5 ug)/per test. A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary
Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
CD172A / SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases.
Staining of normal human peripheral blood cells with APC Mouse IgG2a isotype control (left) or APC anti-human CD172a (right). Cells in the lymphocyte (green histogram) and granulocyte (blue histogram) gates were used for analysis.
Requested From: United States
Date Requested: 10/21/2016