Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Goat Polyclonal to Human SH2D1A / SAP
Human, Monkey, Pig
Western blot, ELISA
Human SH2D1A / SAP
Human, Monkey, Pig (tested or 100% immunogen sequence identity)
Bat, Bovine, Horse, Rabbit (at least 90% immunogen sequence identity)
Western blot (0.2 - 0.6 µg/ml)
Specificity and Use
SH2D1A / SAP antibody was raised against synthetic peptide C-QYPVEKKSSARSTQ from an internal region of human SH2D1A / SAP (NP_002342.1; NP_001108409.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Pig (100%); Bat, Bovine, Horse, Rabbit (93%); Tamarin, Rat (86%).
LS-E25988 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55461. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
SH2D1A / SAP is a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site.