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Anti-SETDB2 Antibody (aa174-188) LS-C154843

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SETDB2 Antibodies

Anti-SETDB2 Antibody (aa174-188) LS-C154843
Goat Polyclonal to Human SETDB2
Human, Monkey, Mouse, Bat, Bovine, Dog, Horse, Rabbit
Western blot, ELISA
Unconjugated
Western blot Image
Anti-SETDB2 Antibody (aa620-720, Biotin) LS-C282653
Mouse Monoclonal (IgG2a) to Human SETDB2
Human
Western blot, ELISA
Biotin Conjugated
Anti-SETDB2 Antibody (aa620-720, FITC) LS-C282654
Mouse Monoclonal (IgG2a) to Human SETDB2
Human
Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human SETDB2
Human, Monkey, Mouse, Bat, Bovine, Dog, Horse, Rabbit
Western blot, ELISA
Unconjugated

Details

Human SETDB2
Goat
Human, Monkey, Mouse, Bat, Bovine, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Guinea pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.1 - 0.3 µg/ml)
  • ELISA (1:32000)

Specificity and Use

SETDB2 antibody was raised against synthetic peptide C-QRRHAKTNSHSSALH from the C or N-terminus of human SETDB2 (NP_114121.2; NP_001153780.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Bovine, Bat, Dog, Horse, Rabbit, Porcine (100%); Elephant, Panda, Guinea pig (93%); Platypus (87%).
LS-E27649 - Lyophilized - 100 µg - $145.00
aa174-188
Human SETDB2. This antibody is expected to recognize both reported isoforms (NP_114121.2; NP_001153780.1).
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 90kD band observed in Human Heart lysates (calculated MW of 81.9kD according to NP_114121.2). Recommended concentration: 0.1-0.3 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SETDB2

NM_031915

SETDB2 Antibody, C13orf4 Antibody, CLLD8 Antibody, CLLL8 Antibody, KMT1F Antibody, Lysine N-methyltransferase 1F Antibody, SET domain bifurcated 2 Antibody, SET domain, bifurcated 2 Antibody

Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

Western blot

Western blot
SETDB2 antibody (0.1 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/10/2016

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