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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SETD8 / SET8 Antibody LS‑C126149
Antibody
SET8 antibody LS-C126149 is an unconjugated rabbit polyclonal antibody to human SET8 (SETD8). Validated for ICC and WB.
Catalog
Size
Price
LS-C126149-100
100 µl
Unavailable

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Product Description

SET8 antibody LS-C126149 is an unconjugated rabbit polyclonal antibody to human SET8 (SETD8). Validated for ICC and WB.
About SETD8 / SET8
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Q9NQR1 NM_020382 NP_065115.3

SETD8 Antibody, KMT5A Antibody, Lysine N-methyltransferase 5A Antibody, PR/SET07 Antibody, PRSET7 Antibody, SET8 Antibody, H4-K20-HMTase SETD8 Antibody, PR-Set7 Antibody, SET07 Antibody


Specifications

Target
Human SETD8 / SET8
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot (1:1000)
  • (applications tested for the base form of this product only)
Immunogen
SETD8 / SET8 antibody was raised against gST-tagged recombinant protein corresponding to human SETD8 (hPR-SET7).
Specificity
Recognizes human SETD8. Species sequence homology: mouse, rat (100%).
Usage
Suitable for use in Western Blot and Immunocytochemistry. Western Blot: 1:1000.
Presentation
0.1 M Tris-glycine, pH 7.4, 0.15 mM sodium chloride, 0.05% sodium azide
Storage
May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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