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Anti-SET / TAF-I Antibody (aa66-81) IHC-plus™ LS-B2058

Note: This antibody replaces LS-C727

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SET / TAF-I Antibodies

Anti-SET / TAF-I Antibody (aa66-81) IHC-plus™ LS-B2058
Rabbit Polyclonal (IgG) to Human SET / TAF-I
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Pig, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SET / TAF-I Antibody (clone M1-F5) LS-C198177
Mouse Monoclonal [clone M1-F5] (IgG1,k) to Human SET / TAF-I
Human
Immunofluorescence, Western blot, ELISA
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human SET / TAF-I
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Pig, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated

Details

Human SET / TAF-I
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Pig, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (1 - 2 µg/ml)

Specificity and Use

SET / TAF-I antibody was raised against synthetic peptides of amino acids 66-81 (PFFQKRSELIAKIPNF) and 135-151 (ENKVLSKEFHLNESGDP) of human INHAT-1. Sequence homology is 100% in mouse and rat. Percent identity by BLAST analysis: Human, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus, Salmon, Pufferfish, Zebrafish (100%); Gorilla, Stickleback (94%); Dog (88%).
aa66-81
An approx. 37 kD band is observed.
Immunohistochemistry: LS-B2058 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2058 was determined to be 10 ug/ml.

Packaging

PBS, 0.02% sodium azide, 0.1 mg/ml BSA. sodium azide is toxic.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About SET / TAF-I

Q01105 NM_003011 NP_003002.2

SET Antibody, 2PP2A Antibody, HLA-DR-associated protein II Antibody, I-2PP2A Antibody, TAF-IBETA Antibody, SET nuclear oncogene Antibody, TAF-I Antibody, Template-activating factor I Antibody, I2PP2A Antibody, IGAAD Antibody, IPP2A2 Antibody, PHAPII Antibody, Protein SET Antibody

Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A.

Immunohistochemistry

Immunohistochemistry
Anti-SET antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2058 concentration 10 ug/ml.

Western blot

Western blot
Western blot of INHAT-1 using antibody against Jurkat cell lysate.

Requested From: United States
Date Requested: 12/6/2016

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