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Anti-SET / TAF-I Antibody (aa2-15) IHC-plus™ LS-B4032

Note: This antibody replaces LS-C55456

Ordering

Wt. Vol. Conc. Price
50 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SET / TAF-I Antibodies

Anti-SET / TAF-I Antibody (aa66-81) IHC-plus™ LS-B2058
Rabbit Polyclonal (IgG) to Human SET / TAF-I
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Pig, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SET / TAF-I Antibody (clone M1-F5) LS-C198177
Mouse Monoclonal [clone M1-F5] (IgG1,k) to Human SET / TAF-I
Human
Immunofluorescence, Western blot, ELISA
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human SET / TAF-I
Human, Bovine, Chicken
IHC - Paraffin, Western blot
Unconjugated

Details

Human SET / TAF-I
Goat
Human, Bovine, Chicken (tested or 100% immunogen sequence identity)
Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (1 - 3 µg/ml)

Specificity and Use

SET / TAF-I antibody was raised against synthetic peptide SAPAAKVSKKELNS-C from the N-terminus of human SET (NP_003002.2). Percent identity by BLAST analysis: Human, Bovine, Opossum, Chicken (100%); Xenopus, Pufferfish, Zebrafish (93%); Mouse, Rat (86%).
LS-E25238 - Lyophilized - 100 µg - $145.00
aa2-15
Human SET. This antibody is expected to recognize isoform 2 (NP_003002.2).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SET / TAF-I

Q01105 NM_003011 NP_003002.2

SET Antibody, 2PP2A Antibody, HLA-DR-associated protein II Antibody, I-2PP2A Antibody, TAF-IBETA Antibody, SET nuclear oncogene Antibody, TAF-I Antibody, Template-activating factor I Antibody, I2PP2A Antibody, IGAAD Antibody, IPP2A2 Antibody, PHAPII Antibody, Protein SET Antibody

Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A.

Immunohistochemistry

Immunohistochemistry
Anti-SET antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4032 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-SET antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4032 concentration 3.75 ug/ml.

Western blot

Western blot
Antibody staining (2 ug/ml) of Human Kidney extracts (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
 

Requested From: United States
Date Requested: 12/2/2016

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