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SERPINB9 / PI9 is a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.
Gene Name: | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
Synonyms: | SERPINB9, CAP-3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, Serpin B9, PI-9, PI9 |
Target Sequences: | NM_004155 NP_004146.1 P50453 |
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