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Anti-SEMA4D / Semaphorin 4D / CD100 Antibody LS-C43410

Note: This antibody replaces LS-C57269, LS-C43408

Catalog	Size	Price
LS-C43410-100	100 µg (1 mg/ml)	Unavailable

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91 SEMA4D / Semaphorin 4D / CD100 Antibodies

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Anti-SEMA4D / Semaphorin 4D / CD100 Antibody (Biotin) LS-C35789

Antibody:	Mouse Monoclonal (IgM) to Human SEMA4D / Semaphorin 4D / CD100
Reactivity:	Human
Application:	IHC - Frozen, Flow Cytometry
Format:	Biotin Conjugated

Anti-SEMA4D / Semaphorin 4D / CD100 Antibody (clone A8, APC) LS-C57266

Antibody:	Mouse Monoclonal [clone A8] (IgG1) to Human SEMA4D / Semaphorin 4D / CD100
Reactivity:	Human, Cynomolgus monkey, Rhesus monkey
Application:	Western blot, Immunoprecipitation, Flow Cytometry
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Anti-SEMA4D / Semaphorin 4D / CD100 Antibody (APC) LS-C78811

Antibody:	Mouse Monoclonal (IgG1) to Human SEMA4D / Semaphorin 4D / CD100
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Application:	Flow Cytometry
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Anti-SEMA4D / Semaphorin 4D / CD100 Antibody (clone 133-1C6, Biotin) LS-C134691

Antibody:	Mouse Monoclonal [clone 133-1C6] (IgM) to Human SEMA4D / Semaphorin 4D / CD100
Reactivity:	Human
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Anti-SEMA4D / Semaphorin 4D / CD100 Antibody (clone C4D204) LS-C191694

Antibody:	Mouse Monoclonal [clone C4D204] (IgG1) to Human SEMA4D / Semaphorin 4D / CD100
Reactivity:	Human
Application:	IHC - Paraffin
Format:	Unconjugated

Antibody:	Mouse Monoclonal (IgG1) to Human SEMA4D / Semaphorin 4D / CD100
Reactivity:	Human, Cynomolgus monkey, Rhesus monkey
Application:	Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Human SEMA4D / Semaphorin 4D / CD100
Host:	Mouse
Reactivity:	Human, Cynomolgus monkey, Rhesus monkey (tested or 100% immunogen sequence identity)
Clonality:	IgG1 Monoclonal
Conjugations:	Unconjugated. Also available conjugated with FITC, RPE, APC.
Purification:	Purified
Modifications:	Unmodified. Also available Low Endotoxin.

Applications

Approved:

Western blot
Immunoprecipitation
Flow Cytometry (1:1)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:	SEMA4D / Semaphorin 4D / CD100 antibody was raised against human PHA activated lymphocytes.
Specificity:	Recognizes human Sepaphorin 4D, also known as CD100, A8, BB18 or GR3. CD100 is a 841 amino acid ~150 kD homodimeric single pass type 1 transmembrane cell surface glycoprotein actin as a receptor for some members of the plexin family. CD100 is expressed at low levels by peripheral blood T cells, and at higher density on activated T cells and B cells, it is also expresses at high levels in fetal kidney with lower levels in fetal brain, liver and lung.
Usage:	Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

Presentation:	PBS, pH 7.4, 0.09% sodium azide.
Storage:	+4°C or -20°C, Avoid repeated freezing and thawing.
Restrictions:	For research use only.

About SEMA4D / Semaphorin 4D / CD100

Uniprot: Q92854 NCBI: NM_006378 NP_006369.3

Synonyms: SEMA4D Antibody, A8 Antibody, BB18 Antibody, C9orf164 Antibody, CD100 antigen Antibody, Coll-4 Antibody, GR3 Antibody, Semaphorin-4D Antibody, M-sema-G Antibody, SEMAJ Antibody, CD100 Antibody

Description: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro).

(More About SEMA4D / Semaphorin 4D / CD100)

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