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Human SEMA4D / Semaphorin 4D / CD100 | |
Mouse | |
Human, Cynomolgus monkey, Rhesus monkey (tested or 100% immunogen sequence identity) | |
IgG1 Monoclonal | |
Unconjugated. Also available conjugated with FITC, RPE, APC. | |
Purified | |
Unmodified. Also available Low Endotoxin. |
Human PHA activated lymphocytes. | |
Recognizes human Sepaphorin 4D, also known as CD100, A8, BB18 or GR3. CD100 is a 841 amino acid ~150 kD homodimeric single pass type 1 transmembrane cell surface glycoprotein actin as a receptor for some members of the plexin family. CD100 is expressed at low levels by peripheral blood T cells, and at higher density on activated T cells and B cells, it is also expresses at high levels in fetal kidney with lower levels in fetal brain, liver and lung. | |
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request. |
PBS, pH 7.4, 0.09% sodium azide. | |
+4°C or -20°C, Avoid repeated freezing and thawing. | |
For research use only. |
SEMA4D Antibody, A8 Antibody, BB18 Antibody, C9orf164 Antibody, CD100 antigen Antibody, Coll-4 Antibody, GR3 Antibody, Semaphorin-4D Antibody, M-sema-G Antibody, SEMAJ Antibody, CD100 Antibody
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro).