Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
SELN / SEPN1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene Name: | selenoprotein N, 1 |
Synonyms: | SEPN1, CFTD, MDRS1, RSMD1, RSS, Selenoprotein N, 1, Selenoprotein N, SELN |
Target Sequences: | AF166125 AAF21430.1 Q9NZV5 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.