Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone DREG-56 (DREG56)] (IgG1,k) to Human SELL / L-Selectin / CD62L
IHC - Frozen, Western blot, Flow Cytometry
Human SELL / L-Selectin / CD62L
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [DREG-56 (DREG56)]
IHC - Frozen
IHC - Paraffin
Specificity and Use
SELL / L-Selectin / CD62L antibody was raised against human SELL
The DREG-56 (DREG56) antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
SELL / L-Selectin / CD62L is a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.
Staining of normal human peripheral blood cells with 0.5 ug of Purified Mouse IgG1, K isotype control (open histogram) or 0.5 ug of Purified anti-human CD62L (Dreg 56) (colored histogram) followed by FITC Anti-Mouse IgG. Cells in the lymphocyte gate were used for analysis.
Requested From: United States
Date Requested: 2/27/2017