Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human SELL / L-Selectin / CD62L
IHC - Frozen, Flow Cytometry, ELISA
Human SELL / L-Selectin / CD62L
Human (tested or 100% immunogen sequence identity)
IHC - Frozen, Flow Cytometry (1:20), ELISA
Specificity and Use
Recognizes human CD62L (L-selectin).
Suitable for use in ELISA, Flow Cytometry and Immunohistochemistry. Immunohistochemistry (frozen): acetone-fixed cryostat sections or cell smears. Flow Cytometry: 1:20 as determined on RPMI8866 cells. Can be used in a 2-step procedure using the biotin- (strep)avidin system.
50 mM Tris, pH 7.4, 100 mM sodium chloride, 1% BSA; 0.02% sodium azide. Labeled wtih biotin.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
SELL / L-Selectin / CD62L is a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.