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Anti-Secretory Component Antibody LS-C147807

Ordering

Wt. Vol. Conc. Price
- 1000 µl - Unavailable

Most Popular Secretory Component Antibodies

Anti-Secretory Component Antibody (clone SC-05) LS-C45754
Mouse Monoclonal [clone SC-05] (IgG1) to Human Secretory Component
Human
IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated
Anti-Secretory Component Antibody LS-C76982
Sheep Polyclonal (IgG) to Rabbit Secretory Component
Rabbit
Western blot, ELISA
Unconjugated
Anti-Secretory Component Antibody (clone SC-05) LS-C146617
Mouse Monoclonal [clone SC-05] (IgG1) to Human Secretory Component
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed
Sheep Polyclonal to Human Secretory Component
Human
Immunodiffusion
Unconjugated

Details

Human Secretory Component
Sheep
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity absorbed
Unmodified

Applications

Immunodiffusion

Specificity and Use

Human secretory IgA
Human IgA Secretory Component (IgAs). The reactivity of the antiserum is restricted to the Fc part of the IgA molecule and to surface and hidden determinants of the secretory component as tested in immunoelectrophoresis and radial immunodiffusion. In immunoelectrophoresis using various antiserum concentrations against normal human milk two precipitin lines may be obtained, one representing IgA and the other the free secretory component. Against normal human serum only IgA is precipitated. No precipitation reaction is obtained with purified IgG, IgM, and IgG/Fab fragments. Cross-reactivity The antiserum does not cross-react with any other component of the human Ig system. Inter- species cross-reactivity is a normal feature of antibodies to immunoglobulins, since Ig of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.
This product is intended for use in precipitating techniques as immunoelectrophoresis and radial immunodiffusion to identify the presence of IgA in human serum, milk or other body fluids or to determine its concentration. To prepare an immunoadsorbent for the purification of human IgA from serum or exocrine secretions. Antisera to IgA do not discriminate between serum IgA (monomeric and dimeric) and higher molecular forms as secretory IgA. This antiserum is not intended for use in non-precipitating antibody-binding or other highly sensitive assays. This does not exclude such use if proper controls are include.

Packaging

Lyophilized antiserum
1,000 µl Sterile distilled water 1 ml
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About Secretory Component

Secretory Component is a component of immunoglobulin A (IgA) which consists of a portion of the polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis. The receptor-IgA complex passes through the cellular compartments before being secreted on the luminal surface of the epithelial cells, still attached to the receptor.

Requested From: 
Date Requested: 3/28/2017

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