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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SDF1 / CXCL12 Antibody LS‑C48888
Antibody
CXCL12 antibody LS-C48888 is an unconjugated rabbit polyclonal antibody to CXCL12 (SDF1) from mouse and rat. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C48888-30
30 µg
Unavailable
LS-C48888-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

CXCL12 antibody LS-C48888 is an unconjugated rabbit polyclonal antibody to CXCL12 (SDF1) from mouse and rat. Validated for IHC, IP and WB.
About SDF1 / CXCL12
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. P48061 NM_000609 NP_000600.1

CXCL12 Antibody, C-X-C motif chemokine 12 Antibody, HIRH Antibody, IRH Antibody, SDF-1 Antibody, SDF-1b Antibody, SDF1A Antibody, SDF1B Antibody, TPAR1 Antibody, TLSF-a Antibody, TLSF-b Antibody, SDF-1a Antibody, SDF1 Antibody, Sdf1alpha Antibody, Stromal cell-derived factor 1 Antibody, TLSF Antibody, HSDF-1 Antibody, PBSF Antibody, SCYB12 Antibody


Specifications

Target
Mouse SDF1 / CXCL12
Host
Rabbit
Reactivity
Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Immunogen
SDF1 / CXCL12 antibody was raised against e. coli-expressed mouse SDF-1 beta.
Specificity
The antibody can be used for Western blot analysis (1 ug/ml), immunoprecipitation (4-8 ug/ml), and immunohistochemistry (10-20 ug/ml). Cross-reactivity to SDF-1 beta of other species has not been determined
Presentation
PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal.
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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