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Anti-S100A9 / MRP14 Antibody (clone S36-48, Biotin) LS-C96227

Ordering

Wt. Vol. Conc. Price
100 µg - - $545
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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866-206-6909
Orders@LSBio.com
 

Most Popular S100A9 / MRP14 Antibodies

Anti-S100A9 / MRP14 Antibody (clone 47-8D3) IHC-plus™ LS-B6597
Mouse Monoclonal [clone 47-8D3] (IgG1) to Human S100A9 / MRP14
Human
IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-S100A9 / MRP14 Antibody (C-Terminus) IHC-plus™ LS-B6742
Rabbit Polyclonal to Human S100A9 / MRP14
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-S100A9 / MRP14 Antibody (C-Terminus) LS-C153526
Rabbit Polyclonal to Human S100A9 / MRP14
Human, Mouse
IHC, Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone S36-48] to Human S100A9 / MRP14
Human
IHC - Paraffin, ELISA
Biotin Conjugated

Details

Human S100A9 / MRP14
Mouse
Human (tested or 100% immunogen sequence identity)
Monoclonal [S36-48]
Biotin
Affinity purified
Unmodified

Applications

  • IHC - Paraffin
  • ELISA

Specificity and Use

S100A9 / MRP14 antibody was raised against cultured human monocytes
The antigen is MRP14, the epitope is suspected in the central region of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes. It is absent from all other blood cells. In cultured monocytes, maximum MRP14 expression is found after 3 - 4 days. Myeloid leukaemic cells have been found to be positive as well. Tissue sections: MRP14 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP14 increasingly during the early stages of inflammation. A high MRP14 (and low MRP8) expression by macrophages was reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases like chronic rheumatoid arthritis, MRP8 and MRP14 positive cells consist of different subpopulations. During early inflammation endothelial cells are also positive with MRP8/14 determined by antibody 27E10. Specificity: Human: MRP14, granulocytes, stimulated monocytes and macrophages. Other: The antibody reacts with bovine spleen. It does not react with swine tissues.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
0.5ml distilled water
Store at 4°C.
For research use only.

About S100A9 / MRP14

P06702 NM_002965 NP_002956.1

S100A9 Antibody, 60B8AG Antibody, Calgranulin B Antibody, CFAG Antibody, CAGB Antibody, Calgranulin-B Antibody, Calprotectin L1H subunit Antibody, CGLB Antibody, L1Ag Antibody, MRP14 Antibody, NIF Antibody, p14 Antibody, Protein S100-A9 Antibody, LIAG Antibody, MAC387 Antibody, MRP-14 Antibody

S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.

Requested From: United States
Date Requested: 12/9/2016

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