Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone CF-557] (IgG1) to Human S100A9 / MRP14
Human S100A9 / MRP14
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CF-557]
Protein G purified
Flow Cytometry (2 µg/10E6 cells)
Specificity and Use
S100A9 / MRP14 antibody was raised against purified granulocyte antigen of human origin.
Anti-Human Calgranulin B monoclonal antibody reacts with the human Calgranulin B protein. Calgranulin B, also known as MRP-14 and S 100A9 is a member of the S100 family of proteins containing 2 EF hand (alpha helix, turn, alpha helix structure) calcium bi.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.