Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone P4/16] (IgG2b) to Rat RT6.1 Alloantigen
Rat RT6.1 Alloantigen
Rat (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [P4/16]
Flow Cytometry (1:1 - 1:10)
Specificity and Use
PVG lymphoid cells.
Recognizes the RT6.1 alloantigen also known as ART2, Pta. A2, and Ag-F1. RT6 is expressed on most peripheral T cells but not on thymocytes. Clone P4/16 recognizes rat strains expressing RT6.1 including BUF, LEW, and PVG and will not recognize RT6.2 expressing strains such as AUG, BDIX, DA and F344.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.