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Anti-RPS6KA3 / RSK2 Antibody (aa604-617) IHC-plus™ LS-B3676

Note: This antibody replaces LS-C63199

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RPS6KA3 / RSK2 Antibodies

Anti-RPS6KA3 / RSK2 Antibody (phospho-Ser369) LS-C96796
Rabbit Polyclonal to Human RPS6KA3 / RSK2
Human
Dot Blot
Unconjugated
Dot Blot Image
Anti-RPS6KA3 / RSK2 Antibody (aa604-617) IHC-plus™ LS-B3676
Rabbit Polyclonal to Mouse RPS6KA3 / RSK2
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-RPS6KA3 / RSK2 Antibody (C-Terminus) IHC-plus™ LS-B7708
Rabbit Polyclonal to Mouse RPS6KA3 / RSK2
Mouse, Human, Rat, Bovine, Dog, Chicken
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse RPS6KA3 / RSK2
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated

Details

Mouse RPS6KA3 / RSK2
Rabbit
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (20 µg/ml)
  • Western blot (1 µg/ml)
  • Immunoprecipitation

Specificity and Use

RPS6KA3 / RSK2 antibody was raised against a 14 residue synthetic peptide (C)NRNQSPVLEPVGRS based on the mouse RSK2 S6 kinase (amino acids 604-617) with the cysteine (C) residue added and the peptide coupled to KLH. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%).
aa604-617
Detects an ~90 kD protein, corresponding to the apparent molecular mass of RSK2 on SDS-PAGE immunoblots, in samples from mouse and rat origins.
Immunohistochemistry: LS-B3676 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3676 was determined to be 20 ug/ml.

Packaging

PBS, pH 7.2, 50% glycerol, 0.09% azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
For research use only.

About RPS6KA3 / RSK2

P51812 NM_004586 NP_004577.1

RPS6KA3 Antibody, Coffin-Lowry syndrome Antibody, HU-2 Antibody, ISPK1 Antibody, MAPKAP kinase 1B Antibody, MAPKAPK-1b Antibody, MRX19 Antibody, Ribosomal S6 kinase 2 Antibody, RSK-2 Antibody, p90-RSK 3 Antibody, p90RSK3 Antibody, RSK Antibody, RSK2 Antibody, S6K-alpha-3 Antibody, S6K-alpha3 Antibody, CLS Antibody, ISPK-1 Antibody, MAPKAPK1B Antibody, p90-RSK2 Antibody, Pp90RSK2 Antibody

Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1.

Immunohistochemistry

Immunohistochemistry
Anti-RPS6KA3 / RSK2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3676 concentration 20 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-RPS6KA3 / RSK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3676 concentration 20 ug/ml.

Requested From: United States
Date Requested: 12/9/2016

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