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Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.
Gene Name: | Ras-like without CAAX 1 |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | RIT1, GTP-binding protein Rit1, GTP-binding protein Roc1, Ras-like without CAAX 1, RIBB, RIT, ROC1 |
Target Sequences: | NM_006912 NP_008843.1 Q92963 |
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