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Anti-RIPK3 / RIP3 Antibody (aa473-486) LS-C93312

Ordering

Wt. Vol. Conc. Price
100 µg - - $650
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RIPK3 / RIP3 Antibodies

Anti-RIPK3 / RIP3 Antibody (aa480-530) IHC-plus™ LS-B1769
Rabbit Polyclonal (IgG) to Human RIPK3 / RIP3
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-RIPK3 / RIP3 Antibody (aa489-518) LS-C97217
Rabbit Polyclonal to Human RIPK3 / RIP3
Human, Mouse
IHC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-RIPK3 / RIP3 Antibody (Internal, Azide-free, HRP) LS-C282304
Rabbit Polyclonal (IgG) to Human RIPK3 / RIP3
Human, Mouse
IHC, Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Mouse RIPK3 / RIP3
Mouse
Western blot
Unconjugated

Details

Mouse RIPK3 / RIP3
Rabbit
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (0.5 - 1 µg/ml)

Specificity and Use

RIPK3 / RIP3 antibody was raised against synthetic peptide AQFGRGRGWQPFHK corresponding to amino acids 473 to 486 of murine RIP3 (3). Percent identity by BLAST analysis: Mouse (100%).
aa473-486
Recognizes mouse RIP3 at ~57kD. Species cross-reactivity: Rat.
Suitable for use in Western Blot. Western Blot: 0.5-1 ug/ml. Positive control: 3T3 cell lysate.

Packaging

PBS, 0.02% sodium azide
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About RIPK3 / RIP3

Q9Y572 NM_006871 NP_006862.2

RIPK3 Antibody, Receptor interacting protein 3 Antibody, RIP-like protein kinase 3 Antibody, RIP3 Antibody, RIP-3 Antibody, Receptor-interacting protein 3 Antibody

Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Requested From: United States
Date Requested: 12/10/2016

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