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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RIPK1 / RIP Antibody (clone 7H10) IHC‑plus™ LS‑B7087
Note: This antibody replaces LS-C62090
RIP antibody LS-B7087 is an unconjugated mouse monoclonal antibody to RIP (RIPK1) from human, mouse and rat. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7087-50
50 µl (1 mg/ml)
Unavailable

Popular RIPK1 / RIP Products

Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, Immunoprecipitation
Anti-RIPK1 /RIP antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4613 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-RIPK1 /RIP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4701 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin
IHC of RIP in formalin-fixed, paraffin-embedded normal human tonsil using LS-C147991 at 1:2000. A, low magnification over view of a secondary follicle. A1 and A2, successively higher magnifications of the germinal center from A. Hematoxylin-Eos in counterstain.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation

Product Description

RIP antibody LS-B7087 is an unconjugated mouse monoclonal antibody to RIP (RIPK1) from human, mouse and rat. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
About RIPK1 / RIP
Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Q13546 NM_003804 NP_003795.2

RIPK1 Antibody, Cell death protein RIP Antibody, Receptor interacting protein Antibody, RIP1 Antibody, RIP Antibody, RIP-1 Antibody, Protein kinase rip Antibody, Receptor-interacting protein 1 Antibody, Rinp Antibody


Specifications

Target
Human RIPK1 / RIP
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [7H10]
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:200)
  • Western blot (1:500 - 1:2000)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
RIPK1 / RIP antibody was raised against recombinant human protein purified from E. coli (His/ABD-RIP1).
Presentation
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Sourced in Ascites.
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.
Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.

Western blot

Immunohistochemistry

Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.
Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.

Western blot

Immunohistochemistry

Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.
Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.

Western blot

Immunohistochemistry

Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.
Anti-RIPK1 /RIP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7087 dilution 1:200.

Western blot



Requested From: 
Date Requested: 6/25/2018

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