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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Rhodopsin / RHO Antibody LS‑C17694
RHO antibody LS-C17694 is an unconjugated mouse monoclonal antibody to RHO (Rhodopsin) from human, mouse and rat. Validated for IF, IHC and WB.
Antibody
Catalog
Size
Price
LS-C17694-500
500 µl (0.2 mg/ml)
$605

Popular Rhodopsin / RHO Products

Anti-RHO / Rhodopsin antibody LS-A1052 IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Pig, Rabbit
Applications: IHC, IHC - Paraffin
Pig retinal section stained with Rhodopsin / RHO antibody (green) and counterstained with rabbit polyclonal antibody to neurofilament RPCA-NF-M (red) and DNA (blue). Rhodopsin is most abundant in the outer segments of retina (OS), NF-M is abundant in the optic nerve fiber layer (ONFL), but seen in processes and neurons in other regions also. Other layers are pigmented epithelium (PE), outer and inner nuclear layers (ONL, INL), outer and inner plexiform layers (OPL, IPL) and ganglion cell layer (GCL).
Species: Human, Mouse, Rat, Bovine, Pig
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Rat
Applications: IHC, Western blot
Anti-Rhodopsin / RHO antibody IHC staining of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10408 concentration 10 ug/ml.
Species: Human, Mouse, Rat, Bovine, Pig
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Antibody
Species: Vertebrate
Applications: IHC, ICC, Western blot, Immunoprecipitation, ELISA

Product Description

RHO antibody LS-C17694 is an unconjugated mouse monoclonal antibody to RHO (Rhodopsin) from human, mouse and rat. Validated for IF, IHC and WB.
About Rhodopsin / RHO
Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. P08100 NM_000539 NP_000530.1

RHO Antibody, CSNBAD1 Antibody, OPN2 Antibody, Rhodopsin Antibody, RP4 Antibody, Opsin 2, rod pigment Antibody, Opsin-2 Antibody


Specifications

Target
Rat Rhodopsin / RHO
Host
Mouse
Reactivity
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Rhodopsin / RHO antibody was raised against membrane preparation from adult rat retina. MW of Antigen: 39kD. Cellular Localization: Cytoplasmic.
Specificity
Recognizes a protein of 39kD identified as rat rhodopsin (opsin). Specifically labels the axons and synaptic pedicles of the rods. Species cross-reactivity: human and mouse.
Usage
Useful in studies of photoreceptor cells. Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Western Blot: 1-2 ug/ml for 2 hours at RT. Immunohistochemistry (Formalin/paraffin): 1:25-1:50 for 60 minutes at RT. Staining of formalin fixed tissue sections requires boiling the tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Positive control: Brain or retina.
Presentation
PBS, pH 7.4, 0.1% Sodium Azide, 0.2% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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