Bovine Rhodopsin / RHO

Mouse

Bovine (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

1D4

Unconjugated

Protein G purified

Unmodified

Bovine rhodopsin.

Recognizes rhodopsin, a pigment of the retina responsible for the formation of photoreceptor cells and the first events in the perception of light. Rhodopsin consists of the protein opsin and a reversibly bound cofactor, retinal, a photoreactive chromophore. Upon light absorption the 11-cis-retinal is isomerized to all-trans retinal, leading to a change in the shape of rhodopsin. The change activates the associated G protein and triggers a second messenger cascade, eventually resulting in the transmission of a nerve impulse to the brain. The trans-retinal is released and converted back into 11-cis-retinal for re-entry into the cycle. Defects in the gene cause various retinopathies such as retinitis pigmentosa and X-linked congenital stationary night blindness.

• IHC - Paraffin (1:100)
• Immunofluorescence
• Western blot (1:1000)
• Immunoprecipitation

10mM HEPES, pH 7.5, 150mM NaCl, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08100 NCBI: NM_000539 NP_000530.1