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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RGMB Antibody LS‑C38871 Best Seller
Antibody
RGMB antibody LS-C38871 is an unconjugated sheep polyclonal antibody to RGMB from human and mouse. Validated for ELISA, IHC and WB.
Catalog
Size
Price
LS-C38871-100
100 µg
Unavailable

Popular RGMB Products

Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with DRAGON (RGMB) Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
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Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA

Product Description

RGMB antibody LS-C38871 is an unconjugated sheep polyclonal antibody to RGMB from human and mouse. Validated for ELISA, IHC and WB.
About RGMB
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. Q6NW40 Q6NW40

RGMB Antibody, DRAGON Antibody, Repulsive guidance molecule B Antibody, RGM domain family member B Antibody, RGM domain family, member B Antibody


Specifications

Target
Mouse RGMB
Host
Sheep
Reactivity
Mouse, Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
RGMB antibody was raised against nS0-derived rmRGM-B.
Specificity
Selected for its ability to recognize RGM-B in the applications listed. In direct ELISAs and Western Blots, shows less than 5% cross-reactivity with rmRGM-A and rmRGM-C.
Usage
Western Blot: This antibody can be used at 0.1-0.2 ug/ml with the appropriate secondary reagents to detect mouse and human RGM-B. The detection limit for rmRGM-B and rhRGM-B is approximately 1 ng/lane under non-reducing and reducing conditions. Immunohistochemistry: This antibody will detect mouse RGM-B in cells and tissues. The working dilution is 2-5 ug/ml. Direct ELISA: This antibody can be used at 0.5-1.0 ug/ml with the appropriate secondary reagents to detect mouse and human RGM-B. The detection limit for rmRGM-B and rhRGM-B is approximately 0.5 ng/well.
Presentation
Lyophilized.
Reconstitution
100 µl deionized water
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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