Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1:500 - 1:1000)
Specificity and Use
RETN / Resistin antibody was raised against synthetic peptide corresponding to aa 94-102 of human resistin.
Specifically recognizes human resistin, a product of white adipose tissue believed to induce insulin resistance in obesity and regulate adipocyte differentiation. This hormone appears to be the link between obesity and type 2 diabetes.
Western Blot: A band of approximately 14 kD is detected.
RETN Antibody, ADSF Antibody, Fizz3 Antibody, Resistin Antibody, RETN1 Antibody, Xcp1 Antibody, RSTN Antibody, Found in inflammatory zone 3 Antibody, HXCP1 Antibody, Resistin delta2 Antibody
RETN / Resistin belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene.