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Anti-RCOR1 / COREST Antibody (clone S72-8) IHC-plus™ LS-B8157

Note: This antibody replaces LS-C150426

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RCOR1 / COREST Antibodies

Anti-RCOR1 / COREST Antibody (C-Terminus) IHC-plus™ LS-B1559
Rabbit Polyclonal (IgG) to Human RCOR1 / COREST
Human, Monkey, Mouse, Bovine, Dog, Guinea pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-RCOR1 / COREST Antibody (aa109-293) IHC-plus™ LS-B8140
Rabbit Polyclonal (IgG) to Human RCOR1 / COREST
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-RCOR1 / COREST Antibody (clone S72-8) IHC-plus™ LS-B8157
Mouse Monoclonal [clone S72-8] (IgG1)
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone S72-8] (IgG1)
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated

Details

RCOR1 / COREST
Mouse
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [S72-8]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Western blot
  • Immunoprecipitation

Specificity and Use

RCOR1 / COREST antibody was raised against fusion protein amino acids 109-293 of human Co-Rest (accession number NP_055971). Includes ELM2 and SANT domains
Detects ~66-80kDa (dependingon gel system used).

Packaging

PBS pH7.4, 50% glycerol and 0.09% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About RCOR1 / COREST

Q9UKL0 NM_015156 NP_055971.2

RCOR1 Antibody, COREST Antibody, Protein CoREST Antibody, REST corepressor 1 Antibody, RCOR Antibody, KIAA0071 Antibody, REST corepressor Antibody

Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval.

Immunohistochemistry

Immunohistochemistry
IHC analysis of C-Rest/ RCOR1 using RCOR1 / COREST antibody, tested on mouse brain. Strong nuclear staining of oligodendrocytes, astrocytes, microglial cells and neurons. Top left Cortex. Bottom right white matter.

Immunohistochemistry

Immunohistochemistry
Anti-COREST antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8157 dilution 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-COREST antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8157 dilution 5 ug/ml.
 

Requested From: United States
Date Requested: 12/3/2016

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