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Anti-RCOR1 / COREST Antibody (aa109-293) IHC-plus™ LS-B8140

Note: This antibody replaces LS-C14592

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RCOR1 / COREST Antibodies

Anti-RCOR1 / COREST Antibody (C-Terminus) IHC-plus™ LS-B1559
Rabbit Polyclonal (IgG) to Human RCOR1 / COREST
Human, Monkey, Mouse, Bovine, Dog, Guinea pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-RCOR1 / COREST Antibody (aa109-293) IHC-plus™ LS-B8140
Rabbit Polyclonal (IgG) to Human RCOR1 / COREST
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-RCOR1 / COREST Antibody (clone S72-8) IHC-plus™ LS-B8157
Mouse Monoclonal [clone S72-8] (IgG1)
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal (IgG) to Human RCOR1 / COREST
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated

Details

Human RCOR1 / COREST
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • ICC
  • Western blot
  • Immunoprecipitation

Specificity and Use

RCOR1 / COREST antibody was raised against gST fusion protein corresponding to residues 109-293 of human CoREST.
aa109-293
Recognizes human CoREST, Mr ~66kD. Species cross-reactivity: Mouse and rat.
Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Add 2.5 ul of 2-mercaptoethanol/100 ul of lysate and boil for 5 minutes to reduce the preparation. Load 20 ug of reduced lysate per lane for minigels. Positive control: A431 Cells, Non-Stimulated in RIPA Buffer, Sample Buffer. Add 2.5 ul of 2-mercaptoethanol/100 ul of lysate and boil for 5 minutes to reduce the preparation. Load 20 ug of reduced lysate per lane for minigels.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

Publications (1)

1
Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, deRoos P, Chaudhry A, Niec RE, Arvey A, Samstein RM, Leslie C, Shaffer SA, Goodlett DR, Rudensky AY. Nature immunology. 2012 Oct;13:1010-9. [Full Text Article] [PubMed:22922362] [PMC:PMC3448012]

About RCOR1 / COREST

Q9UKL0 NM_015156 NP_055971.2

RCOR1 Antibody, COREST Antibody, Protein CoREST Antibody, REST corepressor 1 Antibody, RCOR Antibody, KIAA0071 Antibody, REST corepressor Antibody

Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval.

Immunohistochemistry

Immunohistochemistry
Anti-COREST antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8140 dilution 10 ug/ml.
 

Requested From: United States
Date Requested: 12/4/2016

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