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The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
Gene Name: | retinoblastoma binding protein 6 |
Synonyms: | RBBP6, p2P-R, PACT, RBQ1, MY038, p2PR, Protein P2P-R, RB-binding Q-protein 1, RBQ-1, SNAMA |
Target Sequences: | NM_006910 NP_008841.2 Q7Z6E9 |
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