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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RB1 / Retinoblastoma / RB Antibody (clone XZ133, Azide‑free) LS‑C88264
Antibody
RB antibody LS-C88264 is an unconjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human, mouse and chicken. Validated for IF and IP.
Catalog
Size
Price
LS-C88264-0.1
0.1 ml
Unavailable
LS-C88264-0.2
0.2 ml
Unavailable

Popular RB1 / Retinoblastoma / RB Products

Anti-RB1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1495 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Zebrafish, Fish
Applications: Western blot, ELISA

Product Description

RB antibody LS-C88264 is an unconjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human, mouse and chicken. Validated for IF and IP.
About RB1 / Retinoblastoma / RB
Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. P06400 NM_000321 NP_000312.2

RB1 Antibody, p105-Rb Antibody, Osteosarcoma Antibody, PRb Antibody, Retinoblastoma Antibody, Retinoblastoma 1 Antibody, OSRC Antibody, RB Antibody, Pp110 Antibody


Specifications

Target
Human RB1 / Retinoblastoma / RB
Host
Mouse
Reactivity
Human, Mouse, Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [XZ133]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free. Also available Unmodified.
Applications
  • Immunofluorescence
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Immunogen
Recombinant human Rb protein corresponding to amino acids 387-928.
Specificity
aa 620-665
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
10mM PBS, pH 7.4
Storage
Stable for 36 months when stored at or below 0°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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