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Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
Gene Name: | RAP2B, member of RAS oncogene family |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , RAS oncogene |
Synonyms: | RAP2B, Ras-related protein rap-2b, Small GTP binding protein |
Target Sequences: | NM_002886 NP_002877.2 P61225 |
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