Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
RAP1A antibody was raised against synthetic peptide located between aa69-118 of mouse Rap1a (P62835, NP_663516). Percent identity by BLAST analysis: Human, Chimpanzee, Mouse, Rat, Bovine, Rabbit, Horse, Pig, Guinea pig, Chicken (100%).
Mouse RAP1A / RAP1
Lyophilized from PBS
50 µl Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
RAP1A Antibody, C21KG Antibody, G-22K Antibody, GTP-binding protein smg p21A Antibody, KREV-1 Antibody, KREV1 Antibody, RAP1 Antibody, RAS-related protein RAP1A Antibody, Ras-related protein Rap-1A Antibody, Ras-related protein Krev-1 Antibody, SMGP21 Antibody
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function.